What we research

What we research

Borne’s research is focused on the pregnancy period and the factors and conditions in pregnancy that may lead to preterm birth.

We closely examine the biological processes of pregnancy and childbirth to better understand the significance of changes in the maternal environment throughout pregnancy and to understand the mechanisms involved in normal and abnormal labour.

The pregnancy conditions that we investigate include pre-eclampsia, intrauterine growth restriction, the pathophysiological pathways that trigger the premature onset of labour, the maternal environment to ensure healthy babies, the maternal microbiome and the maternal immune system in pregnancy, the development of the baby during pregnancy, the monitoring of fetal health during pregnancy, monitoring the health of the baby during delivery, preparation for pregnancy to improve outcomes for the baby, and complicated pregnancies such as heart disease, diabetes, HIV/sepsis and other maternal conditions in pregnancy.

Only by studying the normal process can we begin to understand the abnormal, and identify markers of risk in women that are likely to deliver their babies preterm.  This knowledge is fundamental to the development of diagnostic, treatment and prevention strategies for preterm birth.  Only by understanding the mechanisms responsible for preterm labour can we identify potential therapeutic targets and devise effective interventions to help prolong pregnancy in women at high risk of preterm delivery.

We do not directly participate in research associated with assisted conception, maternal health not having an impact on babies and children, and neonatal / perinatal interventions to address the consequences of prematurity.